PRP Research
A pilot study evaluating the effectiveness of platelet-rich plasma therapy for treating degenerative tendinopathies: A randomized control trial with a synchronous observational cohort
Patients receiving PRP reported clinically important improvements in pain, disability and tendon pathology, while those receiving placebo injections did not.
PRP provided safe and efficacious treatment for knee osteoarthritis
This level 1 randomized control trial compared clients who received 3 injections of saline to clients who received a series of 3 PRP treatments.. At 12 months, those who received PRP had a 78% improvement in WOMAC scores while those who received saline injections has a 7% improvement.
Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial
Athletes suffering from high ankle sprains benefit from ultrasound-guided PRP injections with a shorter return to play, re-stabilization of the syndesmosis joint and less long-term residual pain.
Platelet rich plasma versus corticosteroid injection for plantar fasciitis: A comparative study
PRP is as effective as Steroid injection at achieving symptom relief at 3 and 6 months after injection, for the treatment of plantar fasciitis, but unlike Steroid, its effect does not wear off with time. At 12 months, PRP is significantly more effective than Steroid, making it better and more durable than cortisone injection.
Platelet-rich plasma versus corticosteroid injection for recalcitrant lateral epicondylitis: clinical and ultrasonographic evaluation
PRP appeared to enable biological healing of the lesion, whereas corticosteroid injections appeared to provide short-term, symptomatic relief but resulted in tendon degeneration.
Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review
The findings of this study identified that in patients with symptomatic knee osteoarthritis, PRP injection results in significant clinical improvements up to 12 months post injection and provides better pain relief then hyaluronic acid injections.
Efficacy of platelet-rich plasma in the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials
At 6 months post injection, PRP and hyaluronic acid (HA) had similar effects with respect to pain relief and functional improvement. At 12 months postinjection, however, PRP was associated with significantly better pain relief and functional improvement.
Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee
Combining HA and PRP resulted to significantly less pain and less functional limitation compared to HA alone up to 1 year after treatment. HA + PRP combination also resulted in significantly more physical function early in the treatment (1 month and 3 months) as compared to PRP alone.